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NMNAT2 Protein (AA 2-307) (His tag)

NMNAT2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >90 % (SDS-PAGE) SDS
Produktnummer ABIN5564379
  • Target Alle NMNAT2 Proteine anzeigen
    NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 2-307
    Spezies
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses NMNAT2 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Human NMNA2 (aa 2-307) is fused at the N-terminus to a His-tag.
    Reinheit
    >90 % (SDS-PAGE)
    Top Product
    Discover our top product NMNAT2 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Solid
    Konzentration
    Lot specific
    Buffer
    Lyophilized in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl plus 0.025 % CHAPS.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Haltbarkeit
    6 months
  • Target
    NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
    Andere Bezeichnung
    NMNAT2 (NMNAT2 Produkte)
    Synonyme
    zgc:73048 Protein, wu:fj59g01 Protein, NMNAT2 Protein, C1orf15 Protein, PNAT2 Protein, AI843915 Protein, D030041I09Rik Protein, PNAT1 Protein, nicotinamide nucleotide adenylyltransferase 2 Protein, nmnat2 Protein, NMNAT2 Protein, Nmnat2 Protein
    Hintergrund
    Nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. NMNAT2 also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. It is highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. NMNAT2 is also found in the heart, skeletal muscle, pancreas and islets of Langerhans. NMNAT2 is essential for axon growth and survival. Its loss from injured axons may activate Wallerian degeneration (axon degeneration induced by nerve injury), whereas NMNAT overexpression rescues axons from degeneration.
    Molekulargewicht
    ~35kDa (SDS-PAGE)
    UniProt
    Q9BZQ4
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