IL36A/IL1F6 Protein (AA 6-158)
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- Target Alle IL36A/IL1F6 (IL1F6) Proteine anzeigen
- IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 6-158
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Applikation
- SDS-PAGE (SDS)
- Kreuzreaktivität
- Human
- Produktmerkmale
- Human IL-36alpha (aa Lys6-Phe158) is untagged.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IL1F6 Protein
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Interleukin 1 Family, Member 6 (IL1F6) (Active) protein
IL1F6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by reducing SDS-PAGE. Active
Interleukin 1 Family, Member 6 (IL1F6) (AA 1-158) protein (His tag)IL1F6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Interleukin 1 Family, Member 6 (IL1F6) (AA 1-160) protein (His tag)IL1F6 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Interleukin 1 Family, Member 6 (IL1F6) (AA 1-158) protein (GST tag)IL1F6 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Interleukin 1 Family, Member 6 (IL1F6) (AA 1-61) protein (GST tag)IL1F6 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Interleukin 1 Family, Member 6 (IL1F6) (AA 6-158) protein (His tag)Crystallography grade IL1F6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Interleukin 1 Family, Member 6 (IL1F6) (AA 8-160) protein (His tag)Crystallography grade IL1F6 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Solid
- Konzentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Haltbarkeit
- 6 months
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- Target
- IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))
- Andere Bezeichnung
- IL-36alpha (IL1F6 Produkte)
- Synonyme
- Il1f6 Protein, Fil1 Protein, IL-1H1 Protein, IL1RP2 Protein, Il1f9 Protein, Il36a Protein, FIL1 Protein, FIL1(EPSILON) Protein, FIL1E Protein, IL-1F6 Protein, IL1(EPSILON) Protein, IL1F6 Protein, interleukin 36, alpha Protein, interleukin 1 family, member 6 (epsilon) Protein, interleukin 1 family, member 6 Protein, interleukin 36 alpha Protein, Il36a Protein, IL1F6 Protein, IL36A Protein, Il1f6 Protein
- Hintergrund
- IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines has been shown to occur at different sites including the lung and skin and can be derived from diverse cell types including keratinocytes, bronchial epithelium as well as macrophages, monocytes and different T cell subsets. IL-36 family members induce the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination. Recently a novel role for IL-36alpha in the pathogenesis of intestinal inflammation has been reported.
- Molekulargewicht
- ~17kDa
- UniProt
- Q9UHA7
- Pathways
- Cancer Immune Checkpoints
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