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TGFA Protein (Transcript Variant 1)

TGFA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % , as determined by Coomassie stained SDS-PAGE. Func, AbP, PI, STD Active
Produktnummer ABIN5505784
  • Target Alle TGFA Proteine anzeigen
    TGFA (Transforming Growth Factor, alpha (TGFA))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 15
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Quelle
    • 21
    • 4
    • 4
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Applikation
    Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
    Spezifität
    Optimal preservation of protein structure, post-translational modifications and functions.
    Produktmerkmale
    • Recombinant human TGF-alpha (TGFA) (transcript variant 1) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Reinheit
    > 98 % , as determined by Coomassie stained SDS-PAGE.
    Endotoxin-Niveau
    Less than 0.01 ng per μg protein as determined by the LAL method.
    Biological Activity Comment
    The ED50 is 0.1 - 0.4 ng/ml, corresponding to a specific activity of 0.25 - 1.0 x 10^7 units/mg, determined by the dose dependent stimulation of BALB/c-3T3 mouse embryonic fibroblast cells proliferation.
    Top Product
    Discover our top product TGFA Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    > 50 μg/mL
    Buffer
    1 x PBS
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TGFA (Transforming Growth Factor, alpha (TGFA))
    Andere Bezeichnung
    TGF-alpha (TGFA Produkte)
    Synonyme
    TFGA Protein, LOC100009482 Protein, TGF alpha Protein, TGFA Protein, wa-1 Protein, wa1 Protein, RATTGFAA Protein, TGFAA Protein, NV15606 Protein, si:ch211-10e8.7 Protein, transforming growth factor alpha Protein, transforming growth factor alpha L homeolog Protein, transforming growth factor-alpha Protein, transforming growth factor, alpha Protein, TGFA Protein, TGF-A Protein, Tgfa Protein, tgfa.L Protein, LOC100121300 Protein, LOC100009150 Protein, tgfa Protein
    Hintergrund
    TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. [UniProtKB/Swiss-Prot Function]
    Molekulargewicht
    5.5 kDa
    NCBI Accession
    NP_003227
    Pathways
    NF-kappaB Signalweg, RTK Signalweg, EGFR Signaling Pathway
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