BCL7A Protein (His tag)

Produktnummer ABIN5505560

Produktdetails

Target: BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses BCL7A Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Purified recombinant protein of Human B-cell CLL/lymphoma 7A (BCL7A), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.coli, 50 μg (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Aufreinigung: Purified

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))

Andere Bezeichnung: B-cell CLL/lymphoma 7A (BCL7A Produkte)

Synonyme: BCL7 Protein, cb585 Protein, id:ibd1097 Protein, sb:cb585 Protein, wu:fk02d01 Protein, zgc:92023 Protein, 4432415N06Rik Protein, AI448316 Protein, bcl7a Protein, MGC89576 Protein, BCL7A Protein, BCL tumor suppressor 7A Protein, B-cell CLL/lymphoma 7A Protein, B cell CLL/lymphoma 7A Protein, B-cell CLL/lymphoma 7A L homeolog Protein, BCL7A Protein, bcl7a Protein, Bcl7a Protein, bcl7a.L Protein

Hintergrund: This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 24.8 kDa

NCBI Accession: NP_066273