AMH Protein (DYKDDDDK-His Tag)

Produktnummer ABIN5505555

Produktdetails

Target: AMH (Anti-Mullerian Hormone (AMH))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses AMH Protein ist gelabelt mit DYKDDDDK-His Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Purified recombinant protein of human anti-Mullerian hormone (AMH), with C-terminal DDK/His tag, expressed in human cells, 20 μg (C-term DDK/His tag) protein expressed in Human HEK293 cells.
• Produced with end-sequenced ORF clone

Aufreinigung: Purified

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 1 x PBS, pH 7.4, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: AMH (Anti-Mullerian Hormone (AMH))

Andere Bezeichnung: anti-Mullerian hormone (AMH Produkte)

Synonyme: AMH Protein, amh Protein, MIF Protein, MIS Protein, anti-Mullerian hormone Protein, amh Protein, AMH Protein, Amh Protein

Hintergrund: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.

Molekulargewicht: 59 kDa

NCBI Accession: NP_000470

Pathways: Negative Regulation of Hormone Secretion