ALAS1 Protein (His tag)

Produktnummer ABIN5505552

Produktdetails

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ALAS1 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Purified recombinant protein of Human aminolevulinate, delta-, synthase 1 (ALAS1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50 μg (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Aufreinigung: Purified

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Andere Bezeichnung: aminolevulinate, delta-, synthase 1 (ALAS1 Produkte)

Synonyme: ALAS Protein, ALAS3 Protein, ALASH Protein, MIG4 Protein, ALAS-N Protein, Alas-1 Protein, Alas-h Protein, ALAS-H Protein, ALASN Protein, ALAS1 Protein, wu:fb58d01 Protein, wu:fi12g09 Protein, 5'-aminolevulinate synthase 1 Protein, aminolevulinic acid synthase 1 Protein, alanyl-tRNA synthetase protein Protein, aminolevulinate, delta-, synthase 1 Protein, ALAS1 Protein, Alas1 Protein, alas1 Protein, alas1.S Protein, alaS1 Protein

Hintergrund: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 70.4 kDa

NCBI Accession: NP_000679

Pathways: Regulation of Lipid Metabolism by PPARalpha