CD3 epsilon Protein (CD3E) (AA 23-108) (Fc Tag)
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- Target Alle CD3 epsilon (CD3E) Proteine anzeigen
- CD3 epsilon (CD3E)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 23-108
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Spezies
- Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CD3 epsilon Protein ist gelabelt mit Fc Tag.
- Applikation
- Functional Studies (Func)
- Sequenz
- AA 23-108
- Produktmerkmale
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 36 kDa. The protein migrates as 45 kDa under reducing (R) condition (SDS-PAGE).
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CD3E Protein
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CD3 epsilon (CD3E) protein (Fc Tag)
CD3E Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
CD3 epsilon (CD3E) protein (His tag)CD3E Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
CD3 epsilon (CD3E) (AA 23-48) protein (Fc-Avi Tag)CD3E Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD3 epsilon (CD3E) protein (His tag)CD3E Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
CD3 epsilon (CD3E) (AA 23-126) protein (Fc Tag)CD3E Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD3 epsilon (CD3E) (AA 22-48) protein (Fc-Avi Tag)CD3E Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD3 epsilon (CD3E) (AA 23-48) protein (Fc-Avi Tag,Biotin)CD3E Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD3 epsilon (CD3E) (AA 22-48) protein (Fc-Avi Tag,Biotin)CD3E Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD3 epsilon (CD3E) (Active) protein (mFc Tag)CD3E Spezies: Human Wirt: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
CD3 epsilon (CD3E) (AA 23-126) protein (His tag,AVI tag,Biotin)CD3E Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
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- Target
- CD3 epsilon (CD3E)
- Andere Bezeichnung
- CD3 epsilon (CD3E Produkte)
- Synonyme
- cd3e Protein, CD3E Protein, t3e Protein, tcre Protein, AI504783 Protein, CD3 Protein, CD3epsilon Protein, T3e Protein, T3E Protein, TCRE Protein, CD3e molecule Protein, CD3 antigen, epsilon polypeptide Protein, cd3e Protein, CD3E Protein, Cd3e Protein
- Hintergrund
- CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
- Molekulargewicht
- 36 kDa
- UniProt
- P22646
- Pathways
- T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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