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Proteoglycan 3 Protein (PRG3) (AA 18-225) (His tag)

PRG3 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN4370742
  • Target Alle Proteoglycan 3 (PRG3) Proteine anzeigen
    Proteoglycan 3 (PRG3)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 18-225
    Spezies
    • 3
    • 1
    Human
    Quelle
    • 2
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses Proteoglycan 3 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Proteoglycan 3/PRG3 (C-6His)
    Sequenz
    LHLENDAPHL ESLETQADLG QDLDSSKEQE RDLALTEEVI QAEGEEVKAS ACQDNFEDEE AMESDPAALD KDFQCPREED IVEVQGSPRC KTCRYLLVRT PKTFAEAQNV CSRCYGGNLV SIHDFNFNYR IQCCTSTVNQ AQVWIGGNLR GWFLWKRFCW TDGSHWNFAY WSPGQPGNGQ GSCVALCTKG GYWRRAQCDK QLPFVCSFVD HHHHHH
    Produktmerkmale
    Recombinant Human Proteoglycan 3/PRG3 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Leu18-Phe225) of Human PRG3 fused with a polyhistidine tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product PRG3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    3 months
  • Target
    Proteoglycan 3 (PRG3)
    Andere Bezeichnung
    Proteoglycan-3 (PRG3 Produkte)
    Synonyme
    MBP2 Protein, MBPH Protein, proteoglycan 3, pro eosinophil major basic protein 2 Protein, proteoglycan 3 Protein, PRG3 Protein, Prg3 Protein
    Sub Type
    Fusionprotein
    Hintergrund
    Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain. Proteoglycans are a major component of the animal extracellular matrix. PRG3 localizes to the eosinophil secondary granule and is expressed in bone marrow, not detected in placenta. PRG3 has similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, PRG3 can stimulate neutrophil superoxide production and IL8 release, histamine and leukotriene C4 release from basophils.
    Alternative Names: Proteoglycan 3, Eosinophil Major Basic Protein Homolog, Prepro-Major Basic Protein Homolog, Prepro-MBPH, PRG3, MBPH
    Molekulargewicht
    24.6 kDa
    UniProt
    Q9Y2Y8
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