DR3/LARD Protein (AA 20-203) (Fc Tag)
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- Target Alle DR3/LARD (TNFRSF25) Proteine anzeigen
- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 20-203
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Spezies
- Cynomolgus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses DR3/LARD Protein ist gelabelt mit Fc Tag.
- Sequenz
- AA 20-203
- Produktmerkmale
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 46.3 kDa. The protein migrates as 50 kDa under reducing (R) condition (SDS-PAGE).
- Reinheit
- >90 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
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- Target
- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
- Andere Bezeichnung
- DR3 / TNFRSF25 (TNFRSF25 Produkte)
- Synonyme
- APO-3 Protein, DDR3 Protein, DR3 Protein, LARD Protein, TNFRSF12 Protein, TR3 Protein, TRAMP Protein, WSL-1 Protein, WSL-LR Protein, Tnfrsf12 Protein, Wsl Protein, TNFRSF25 Protein, TNF receptor superfamily member 25 Protein, tumor necrosis factor receptor superfamily, member 25 Protein, TNFRSF25 Protein, Tnfrsf25 Protein
- Hintergrund
- Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.
- Molekulargewicht
- 46.3 kDa
- UniProt
- G7NTB5
- Pathways
- Apoptose
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