DLL1 Protein (AA 18-540) (His tag)
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- Target Alle DLL1 Proteine anzeigen
- DLL1 (delta-Like 1 (DLL1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 18-540
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses DLL1 Protein ist gelabelt mit His tag.
- Sequenz
- AA 18-540
- Produktmerkmale
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.4 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product DLL1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 150 mM NaCl, pH 7.5
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
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- Target
- DLL1 (delta-Like 1 (DLL1))
- Andere Bezeichnung
- DLL1 (DLL1 Produkte)
- Synonyme
- X-delta-1 Protein, XDelta1 Protein, Xdelta-1 Protein, delta Protein, delta-1 Protein, delta1 Protein, x-delta Protein, DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, DLL1 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, delta-like 1 Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 L homeolog Protein, delta-like 1 (Drosophila) Protein, delta-like 1 homolog (Drosophila) Protein, dll1 Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, dll1.L Protein, Dlk1 Protein
- Hintergrund
- Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
- Molekulargewicht
- 58.4 kDa
- NCBI Accession
- NP_005609
- Pathways
- Notch Signalweg, Stem Cell Maintenance
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