FNDC4 Protein (AA 41-163, Extracellular Domain)
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- Target Alle FNDC4 Proteine anzeigen
- FNDC4 (Fibronectin Type III Domain Containing 4 (FNDC4))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Extracellular Domain, AA 41-163
- Spezies
- Human, Maus, Ratte, Hund, Affe
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Quelle
- Escherichia coli (E. coli)
- Applikation
- SDS-PAGE (SDS)
- Kreuzreaktivität
- Hund, Human, Affe, Maus, Ratte (Rattus)
- Produktmerkmale
- FNDC4 (extracellular domain, human (aa 45-167) / mouse (aa 41-163)) is untagged. FNDC4 extracellular domain has 100 % identity between human, mouse, rat, dog and monkey.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FNDC4 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with 100 μL sterile water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Haltbarkeit
- 6 months
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- Target
- FNDC4 (Fibronectin Type III Domain Containing 4 (FNDC4))
- Andere Bezeichnung
- FNDC4 (FNDC4 Produkte)
- Synonyme
- 2810430J06Rik Protein, 6330410H20Rik Protein, AB030187 Protein, AI838506 Protein, AW487863 Protein, FRCP1 Protein, Fnmp1 Protein, FNDC4 Protein, fibronectin type III domain containing 4 Protein, Fndc4 Protein, FNDC4 Protein, fndc4 Protein
- Hintergrund
- Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. FNDC4 is an ortholog of FNDC5 with 50 % identity and 86 % similarity compared to Irisin. FNDC4 as well as FNDC5 are extremely well conserved between species. The function of FNDC4 is unknown. The human FNDC4 gene is highly enriched in liver, brain tissue and adipocytes.
- Molekulargewicht
- ~16kDa
- UniProt
- Q9H6D8
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