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FNDC4 Protein (AA 41-163, Extracellular Domain)

FNDC4 Spezies: Human, Maus, Ratte, Hund, Affe Wirt: Escherichia coli (E. coli) Recombinant >95 % (SDS-PAGE) SDS
Produktnummer ABIN2745681
  • Target Alle FNDC4 Proteine anzeigen
    FNDC4 (Fibronectin Type III Domain Containing 4 (FNDC4))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Extracellular Domain, AA 41-163
    Spezies
    Human, Maus, Ratte, Hund, Affe
    Quelle
    • 4
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    SDS-PAGE (SDS)
    Kreuzreaktivität
    Hund, Human, Affe, Maus, Ratte (Rattus)
    Produktmerkmale
    FNDC4 (extracellular domain, human (aa 45-167) / mouse (aa 41-163)) is untagged. FNDC4 extracellular domain has 100 % identity between human, mouse, rat, dog and monkey.
    Reinheit
    >95 % (SDS-PAGE)
    Endotoxin-Niveau
    <0.01EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product FNDC4 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with 100 μL sterile water.
    Konzentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Haltbarkeit
    6 months
  • Target
    FNDC4 (Fibronectin Type III Domain Containing 4 (FNDC4))
    Andere Bezeichnung
    FNDC4 (FNDC4 Produkte)
    Synonyme
    2810430J06Rik Protein, 6330410H20Rik Protein, AB030187 Protein, AI838506 Protein, AW487863 Protein, FRCP1 Protein, Fnmp1 Protein, FNDC4 Protein, fibronectin type III domain containing 4 Protein, Fndc4 Protein, FNDC4 Protein, fndc4 Protein
    Hintergrund
    Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. FNDC4 is an ortholog of FNDC5 with 50 % identity and 86 % similarity compared to Irisin. FNDC4 as well as FNDC5 are extremely well conserved between species. The function of FNDC4 is unknown. The human FNDC4 gene is highly enriched in liver, brain tissue and adipocytes.
    Molekulargewicht
    ~16kDa
    UniProt
    Q9H6D8
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