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DLK1 Protein (AA 1-305, Extracellular Domain) (Fc Tag)

DLK1 Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS Active
Produktnummer ABIN2745647
  • Target Alle DLK1 Proteine anzeigen
    DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    Extracellular Domain, AA 1-305
    Spezies
    • 15
    • 6
    • 1
    • 1
    Maus
    Quelle
    • 9
    • 6
    • 5
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses DLK1 Protein ist gelabelt mit Fc Tag.
    Applikation
    SDS-PAGE (SDS)
    Kreuzreaktivität
    Maus
    Produktmerkmale
    Signal peptide and extracellular domain of mouse DLK1 (aa 1-305) are fused at the C-terminus to the Fc portion of human IgG1.
    Reinheit
    >95 % (SDS-PAGE)
    Endotoxin-Niveau
    <0.1EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product DLK1 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    Inhibits adipogenesis of 3T3L-1 cells. Induces Sox-9 in 3T3L-1 cells.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with 100 μL sterile water.
    Konzentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS + 0.02 % CHAPS.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Haltbarkeit
    6 months
  • Target
    DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
    Andere Bezeichnung
    DLK1 (DLK1 Produkte)
    Synonyme
    DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, Zog Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 homolog (Drosophila) Protein, delta-like 1 (Drosophila) Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, Dlk1 Protein
    Hintergrund
    The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
    Molekulargewicht
    ~75kDa (SDS-PAGE)
    UniProt
    Q09163
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