ZAP70 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2735753

Produktdetails

Target: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ZAP70 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ZAP70 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Andere Bezeichnung: Zap70 (ZAP70 Produkte)

Synonyme: SRK Protein, STCD Protein, STD Protein, TZK Protein, ZAP-70 Protein, 70kDa Protein, AI327364 Protein, Srk Protein, mrtle Protein, mur Protein, zap70 Protein, MGC80670 Protein, MGC88962 Protein, ZAP70 Protein, zgc:110383 Protein, zeta chain of T-cell receptor associated protein kinase 70 Protein, putative tyrosine-protein kinase zap-70 Protein, zeta-chain (TCR) associated protein kinase Protein, zeta chain of T cell receptor associated protein kinase 70 Protein, zeta-chain (TCR) associated protein kinase 70kDa Protein, zeta chain of T cell receptor associated protein kinase 70kDa L homeolog Protein, zeta chain of T cell receptor associated protein kinase 70kDa Protein, tyrosine-protein kinase ZAP-70 Protein, ZAP70 Protein, Smp_149470 Protein, Zap70 Protein, zap70.L Protein, zap70 Protein, LOC707555 Protein, LOC100342021 Protein, LOC100390922 Protein, LOC100542877 Protein

Hintergrund: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Molekulargewicht: 69.7 kDa

NCBI Accession: NP_001070

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway