Exportin 2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2735674

Produktdetails

Target: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Exportin 2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human XPO2 / Exportin-2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Andere Bezeichnung: Xpo2,exportin-2 (CSE1L Produkte)

Synonyme: BcDNA:LD14270 Protein, CAS Protein, CG13281 Protein, Dcas Protein, Dmel\\CG13281 Protein, cas Protein, dcas Protein, l(2)k03902 Protein, CSE1L Protein, XPO2 Protein, Exportin-2 Protein, DKFZp459E1929 Protein, 2610100P18Rik Protein, AA407533 Protein, Capts Protein, Cas Protein, Xpo2 Protein, xpo2 Protein, CSE1 Protein, CAS/CSE1 segregation protein Protein, chromosome segregation 1 like Protein, exportin-2 Protein, chromosome segregation 1-like (S. cerevisiae) Protein, CSE1 chromosome segregation 1-like (yeast) Protein, CSE1 chromosome segregation 1-like L homeolog Protein, Cas Protein, CSE1L Protein, LOC100542094 Protein, cse1l Protein, Cse1l Protein, cse1l.L Protein

Hintergrund: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.

Molekulargewicht: 110.2 kDa

NCBI Accession: NP_001307

Pathways: Protein targeting to Nucleus