USP2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2735099

Produktdetails

Target: USP2 (Ubiquitin Specific Peptidase 2 (USP2))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses USP2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human USP2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: USP2 (Ubiquitin Specific Peptidase 2 (USP2))

Andere Bezeichnung: Usp2 (USP2 Produkte)

Synonyme: UBP41 Protein, USP9 Protein, B930035K21Rik Protein, Ubp41 Protein, UBP-t Protein, UBP46 Protein, ubp52 Protein, ubp66 Protein, zgc:92134 Protein, ubiquitin specific peptidase 2 Protein, ubiquitin specific peptidase 2a Protein, USP2 Protein, Usp2 Protein, usp2a Protein

Hintergrund: This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Molekulargewicht: 45.1 kDa

NCBI Accession: NP_741994