UBE2V1 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2734875

Produktdetails

Target: UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 4

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses UBE2V1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human UBE2V1 / CROC1 (transcript variant 4) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Andere Bezeichnung: Ube2v1,croc1 (UBE2V1 Produkte)

Synonyme: CIR1 Protein, CROC-1 Protein, CROC1 Protein, UBE2V Protein, UEV-1 Protein, UEV1 Protein, UEV1A Protein, 0610011J09Rik Protein, AI256840 Protein, D7Bwg1382e Protein, CROC-1B Protein, ubiquitin conjugating enzyme E2 V1 Protein, ubiquitin-conjugating enzyme E2 variant 1 Protein, UBE2V1 Protein, ube2v1 Protein, Ube2v1 Protein

Hintergrund: Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Molekulargewicht: 16.3 kDa

NCBI Accession: NP_001027459

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades