TXNIP Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2734683

Produktdetails

Target: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TXNIP Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human TXNIP / VDUP1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Andere Bezeichnung: Txnip,vdup1 (TXNIP Produkte)

Synonyme: EST01027 Protein, HHCPA78 Protein, THIF Protein, VDUP1 Protein, Gm348 Protein, Trf3 Protein, TBP2 Protein, TRF3 Protein, 1200008J08Rik Protein, AA682105 Protein, Hyplip1 Protein, Tbp-2 Protein, Vdup1 Protein, sb:cb368 Protein, txnip Protein, thioredoxin interacting protein Protein, TATA box binding protein like 2 Protein, TATA-box binding protein like 2 Protein, thioredoxin interacting protein L homeolog Protein, thioredoxin interacting protein a Protein, TXNIP Protein, Tbpl2 Protein, TBPL2 Protein, Txnip Protein, txnip.L Protein, txnip Protein, txnipa Protein

Hintergrund: This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 43.5 kDa

NCBI Accession: NP_006463

Pathways: Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome