TWIST2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2734652

Produktdetails

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TWIST2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human TWIST2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Andere Bezeichnung: Twist2 (TWIST2 Produkte)

Synonyme: TWIST2 Protein, DERMO1 Protein, FFDD3 Protein, SETLSS Protein, bHLHa39 Protein, Dermo1 Protein, CDERMO-1 Protein, twist family bHLH transcription factor 2 Protein, twist basic helix-loop-helix transcription factor 2 Protein, TWIST2 Protein, Twist2 Protein

Hintergrund: The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found.

Molekulargewicht: 17.9 kDa

NCBI Accession: NP_476527

Pathways: Chromatin Binding