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Tropomyosin Protein (Transcript Variant 5) (Myc-DYKDDDDK Tag)

TPM1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2734382
  • Target Alle Tropomyosin (TPM1) Proteine anzeigen
    Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 5
    Spezies
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 18
    • 5
    • 3
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Tropomyosin Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Tropomyosin-1 (TPM1) (transcript variant 5) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
    Andere Bezeichnung
    Tropomyosin-1 (Tpm1) (TPM1 Produkte)
    Synonyme
    alpha-fTM Protein, Tm7 Protein, tpm1 Protein, MGC84844 Protein, AA986836 Protein, AI854628 Protein, TM2 Protein, Tm3 Protein, Tmpa Protein, Tpm-1 Protein, alpha-TM Protein, Alpha-tm Protein, Tma2 Protein, Tmsa Protein, TPM1 Protein, fb37a09 Protein, tm Protein, wu:fb37a09 Protein, CH1 Protein, alpha-tm Protein, alpha-tropomyosin Protein, C15orf13 Protein, CMD1Y Protein, CMH3 Protein, HTM-alpha Protein, TMSA Protein, TPMA Protein, Tm1 Protein, zgc:171719 Protein, zgc:55951 Protein, zgc:77009 Protein, tropomyosin 1 (alpha) Protein, tropomyosin Protein, tropomyosin 1 Protein, tropomyosin 1, alpha Protein, alpha-tropomyosin Protein, tropomyosin 1 L homeolog Protein, TPM1 Protein, tm7 Protein, Tpm1 Protein, tpma Protein, tpm1.L Protein, Smp_044010.2 Protein, LOC732984 Protein, tpm1 Protein
    Hintergrund
    This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
    Molekulargewicht
    32.7 kDa
    NCBI Accession
    NP_000357
    Pathways
    Regulation of Actin Filament Polymerization
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