THRB Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2733597

Produktdetails

Target: THRB (Thyroid Hormone Receptor, beta (THRB))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses THRB Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human THRB / ERBA2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: THRB (Thyroid Hormone Receptor, beta (THRB))

Andere Bezeichnung: Thrb,erba2 (THRB Produkte)

Synonyme: C-ERBA-2 Protein, C-ERBA-BETA Protein, ERBA2 Protein, GRTH Protein, NR1A2 Protein, PRTH Protein, THR1 Protein, THRB1 Protein, THRB2 Protein, Nr1a2 Protein, T3R[b] Protein, T3Rbeta Protein, Thrb1 Protein, Thrb2 Protein, c-erbAbeta Protein, TR-beta Protein, TR[b]1 Protein, fj24f03 Protein, trb Protein, wu:fj24f03 Protein, CTR BETA 2 Protein, TR-BETA Protein, LOC734147 Protein, thrb Protein, THRB Protein, C-erba-beta Protein, RATT3REC Protein, T3rec Protein, TRbeta Protein, THR Protein, TRbeta1 Protein, thyroid hormone receptor beta Protein, thyroid hormone receptor, beta Protein, thyroid hormone receptor, beta S homeolog Protein, thyroid hormone receptor, beta L homeolog Protein, THRB Protein, Thrb Protein, thrb Protein, thrb.S Protein, thrb.L Protein

Hintergrund: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.

Molekulargewicht: 52.6 kDa

NCBI Accession: NP_001121648

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound