TFE3 Protein (His tag)

Produktnummer ABIN2733466

Produktdetails

Target: TFE3 (Transcription Factor E3 (TFE3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Insect cells (Sf9)

Aufreinigungstag / Konjugat: Dieses TFE3 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human TFE3 (N-term polyhistidine tag) protein expressed in Sf9 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: TFE3 (Transcription Factor E3 (TFE3))

Andere Bezeichnung: Tfe3 (TFE3 Produkte)

Synonyme: RCCP2 Protein, RCCX1 Protein, TFEA Protein, bHLHe33 Protein, F830016E06Rik Protein, Tcfe3 Protein, Tfe-3 Protein, RGD1559642 Protein, cb873 Protein, zgc:109815 Protein, transcription factor binding to IGHM enhancer 3 Protein, transcription factor E3 Protein, transcription factor binding to IGHM enhancer 3 S homeolog Protein, transcription factor binding to IGHM enhancer 3a Protein, TFE3 Protein, Tfe3 Protein, tfe3.S Protein, tfe3a Protein

Hintergrund: Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. [UniProtKB/Swiss-Prot Function]

Molekulargewicht: 62 kDa

NCBI Accession: NP_006512