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TAX1BP3 Protein (Myc-DYKDDDDK Tag)

TAX1BP3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2733250
  • Target Alle TAX1BP3 Proteine anzeigen
    TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))
    Protein-Typ
    Recombinant
    Spezies
    • 4
    • 1
    • 1
    Human
    Quelle
    • 4
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses TAX1BP3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human TAX1BP3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TAX1BP3 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))
    Andere Bezeichnung
    Tax1bp3 (TAX1BP3 Produkte)
    Synonyme
    TIP-1 Protein, 1300011C24Rik Protein, RP23-263M10.10 Protein, tax1bp3 Protein, wu:fb37e03 Protein, wu:fc23g08 Protein, zgc:55513 Protein, Tax1 binding protein 3 Protein, Tax1 (human T cell leukemia virus type I) binding protein 3 Protein, Tax1 (human T-cell leukemia virus type I) binding protein 3 S homeolog Protein, Tax1 (human T-cell leukemia virus type I) binding protein 3 Protein, TAX1BP3 Protein, Tax1bp3 Protein, tax1bp3.S Protein, tax1bp3 Protein
    Hintergrund
    This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molekulargewicht
    13.6 kDa
    NCBI Accession
    NP_055419
    Pathways
    Monocarboxylic Acid Catabolic Process
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