TAPBP Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2733221

Produktdetails

Target: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TAPBP Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Tapasin (TAPBP) (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Andere Bezeichnung: Tapasin (Tapbp) (TAPBP Produkte)

Synonyme: SI:dZ179B20.1 Protein, SI:dZ179B20.3 Protein, SI:dZ179B20.7 Protein, mhc1uda Protein, mhc1ufa Protein, tpsn Protein, zgc:109814 Protein, tapbp Protein, TAPBP Protein, D17Wsu91e Protein, TPN Protein, NGS17 Protein, TAPA Protein, TPSN Protein, TAP binding protein (tapasin), tandem duplicate 1 Protein, TAP binding protein Protein, tapbp.1 Protein, tapbp Protein, TAPBP Protein, Tapbp Protein

Hintergrund: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Molekulargewicht: 45.6 kDa

NCBI Accession: NP_003181