SF3B2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2732607

Produktdetails

Target: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SF3B2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Splicing factor 3b, subunit 2, 145 kDa (SF3B2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Abstract: SF3B2 Produkte

Synonyme: 145kDa Protein, 2610311M13Rik Protein, 2810441F20Rik Protein, B230398H18Rik Protein, SAP145 Protein, SF3b1 Protein, SF3b145 Protein, SF3b150 Protein, SF3B2 Protein, cus1 Protein, sap145 Protein, sf3b145 Protein, sf3b150 Protein, Cus1 Protein, SF3B145 Protein, splicing factor 3b, subunit 2 Protein, splicing factor 3b subunit 2 Protein, splicing factor 3B subunit 2 Protein, splicing factor 3b subunit 2 L homeolog Protein, Sf3b2 Protein, SF3B2 Protein, LOC714747 Protein, sf3b2.L Protein, sf3b2 Protein

Hintergrund: This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.

Molekulargewicht: 100 kDa

NCBI Accession: NP_006833