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SPG20 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

SPG20 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2732507
  • Target Alle SPG20 Proteine anzeigen
    SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 4
    • 1
    Human
    Quelle
    • 3
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses SPG20 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Spartin / SPG20 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SPG20 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
    Andere Bezeichnung
    Spartin,spg20 (SPG20 Produkte)
    Synonyme
    SPARTIN Protein, TAHCCP1 Protein, AI840044 Protein, C79168 Protein, mKIAA0610 Protein, spartin Protein, Spg20 Protein, spg20a Protein, zgc:172059 Protein, spg20b Protein, zgc:153766 Protein, spartin Protein, spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) Protein, spartin a Protein, spartin b Protein, SPART Protein, Spg20 Protein, Spart Protein, sparta Protein, spartb Protein
    Hintergrund
    This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
    Molekulargewicht
    72.7 kDa
    NCBI Accession
    NP_055902
    Pathways
    Regulation of Cell Size, SARS-CoV-2 Protein Interaktom
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