SPAG6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2732491

Produktdetails

Target: SPAG6 (Sperm Associated Antigen 6 (SPAG6))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SPAG6 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SPAG6 / PF16 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SPAG6 (Sperm Associated Antigen 6 (SPAG6))

Andere Bezeichnung: Spag6,pf16 (SPAG6 Produkte)

Synonyme: Repro-SA-1 Protein, pf16 Protein, PF16 Protein, RGD1310892 Protein, zgc:91805 Protein, SPAG6 Protein, repro-sa-1 Protein, DKFZp459D035 Protein, sperm associated antigen 6 Protein, sperm associated antigen 6-like Protein, sperm associated antigen 6 L homeolog Protein, SPAG6 Protein, Spag6l Protein, Spag6 Protein, spag6 Protein, spag6.L Protein

Hintergrund: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 49.5 kDa

NCBI Accession: NP_758442