SORD Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2732375

Produktdetails

Target: SORD (Sorbitol Dehydrogenase (SORD))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SORD Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SORD protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SORD (Sorbitol Dehydrogenase (SORD))

Andere Bezeichnung: Sord (SORD Produkte)

Synonyme: SORD1 Protein, Sdh-1 Protein, Sdh1 Protein, Sodh-1 Protein, SDH Protein, sord Protein, MGC83437 Protein, BmSDH Protein, PSPTO0363 Protein, SODH-1 Protein, RATSDHE1 Protein, SDH2 Protein, Sdh Protein, Sdhe1 Protein, TDH Protein, 4733401P19Rik Protein, AI836084 Protein, CGI-97 Protein, SDS Protein, zgc:63674 Protein, sorbitol dehydrogenase Protein, sorbitol dehydrogenase L homeolog Protein, Sorbitol dehydrogenase Protein, serine dehydratase Protein, SBDS ribosome maturation factor Protein, SORD Protein, Sord Protein, sord.L Protein, sord Protein, Sdh Protein, LOC733025 Protein, polS Protein, RS_RS10765 Protein, sdh Protein, smoS Protein, Rsph17029_1731 Protein, Srd Protein, RSKD131_1411 Protein, SDS Protein, Sds Protein, Sbds Protein

Hintergrund: Sorbitol dehydrogenase (SORD EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1 MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010].

Molekulargewicht: 38.1 kDa

NCBI Accession: NP_003095