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SNAP25 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

SNAP25 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2732308
  • Target Alle SNAP25 Proteine anzeigen
    SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 9
    • 5
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses SNAP25 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human SNAP25 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SNAP25 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Brinkmalm, Brinkmalm, Honer, Moreno, Jakobsson, Mallucci, Zetterberg, Blennow, Öhrfelt: "Targeting synaptic pathology with a novel affinity mass spectrometry approach." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 10, pp. 2584-92, (2014) (PubMed).

    Brinkmalm, Brinkmalm, Honer, Frölich, Hausner, Minthon, Hansson, Wallin, Zetterberg, Blennow, Öhrfelt: "SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease." in: Molecular neurodegeneration, Vol. 9, pp. 53, (2014) (PubMed).

    Kariolis, Miao, Jones, Kapur, Mathews, Giaccia, Cochran: "An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis." in: Nature chemical biology, Vol. 10, Issue 11, pp. 977-83, (2014) (PubMed).

    Chen, Fu, Chen, Hu, Soroka, Prigge, Schmidt, Yan, Major, Chen, Sang: "Ginger compound [6]-shogaol and its cysteine-conjugated metabolite (M2) activate Nrf2 in colon epithelial cells in vitro and in vivo." in: Chemical research in toxicology, Vol. 27, Issue 9, pp. 1575-85, (2014) (PubMed).

  • Target
    SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
    Andere Bezeichnung
    Snap25 (SNAP25 Produkte)
    Synonyme
    RIC-4 Protein, RIC4 Protein, SEC9 Protein, SNAP Protein, SNAP-25 Protein, bA416N4.2 Protein, dJ1068F16.2 Protein, SNAP-25B Protein, SNAP-25a Protein, ric-4 Protein, ric4 Protein, sec9 Protein, snap-25 Protein, Bdr Protein, sp Protein, fj55h11 Protein, snap25 Protein, wu:fj55h11 Protein, Snap Protein, snap25.2 Protein, wu:fj33h05 Protein, synaptosome associated protein 25 Protein, synaptosome associated protein 25kDa S homeolog Protein, synaptosomal-associated protein, 25kDa Protein, synaptosomal-associated protein 25 Protein, synaptosome associated protein 25kDa Protein, synaptosome associated protein 25kDa L homeolog Protein, zgc:101731 Protein, synaptosomal-associated protein, 25b Protein, SNAP25 Protein, Snap25 Protein, snap25.S Protein, snap25 Protein, BACOIKO003_07 Protein, Tsp_10811 Protein, snap25.L Protein, zgc:101731 Protein, snap25b Protein
    Hintergrund
    Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
    Molekulargewicht
    23.2 kDa
    NCBI Accession
    NP_003072
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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