SEC31A Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2731578

Produktdetails

Target: SEC31A (SEC31 Homolog A (SEC31A))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 3

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SEC31A Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SEC31A (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SEC31A (SEC31 Homolog A (SEC31A))

Andere Bezeichnung: Sec31a (SEC31A Produkte)

Synonyme: ABP125 Protein, ABP130 Protein, HSPC334 Protein, SEC31L1 Protein, Sec31l1 Protein, VAP1 Protein, 1810024J13Rik Protein, AU042160 Protein, HSPC275 Protein, cb354 Protein, sec31p Protein, zgc:63547 Protein, SEC31 homolog A, COPII coat complex component Protein, Sec31 homolog A (S. cerevisiae) Protein, SEC31A Protein, Sec31a Protein, sec31a Protein

Hintergrund: The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 131.4 kDa

NCBI Accession: NP_001070676

Pathways: ER-Nucleus Signaling