SAG Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2731282

Produktdetails

Target: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SAG Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human S-arrestin / SAG protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Andere Bezeichnung: S-Arrestin,sag (SAG Produkte)

Synonyme: RP47 Protein, S-AG Protein, MGC75721 Protein, MGC84416 Protein, sag Protein, zgc:114197 Protein, SAGMR Protein, SANTI Protein, ARR Protein, sag1 Protein, A930001K18Rik Protein, Arr1 Protein, Irbp Protein, arrestin Protein, S-antigen visual arrestin Protein, S-antigen Protein, S-antigen; retina and pineal gland (arrestin) Protein, S-antigen; retina and pineal gland (arrestin) S homeolog Protein, S-antigen; retina and pineal gland (arrestin) b Protein, S-antigen, retina and pineal gland (arrestin) Protein, S-antigen; retina and pineal gland (arrestin) L homeolog Protein, SAG Protein, PF10_0343 Protein, sag Protein, sag.S Protein, sagb Protein, Sag Protein, sag.L Protein

Hintergrund: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.

Molekulargewicht: 44.9 kDa

NCBI Accession: NP_000532

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling