RORC Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2731080

Produktdetails

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RORC Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ROR-gamma / RORC (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Andere Bezeichnung: Ror-Gamma,rorc (RORC Produkte)

Synonyme: NR1F3 Protein, RORG Protein, RZR-GAMMA Protein, RZRG Protein, TOR Protein, Nr1f3 Protein, RORgamma Protein, Thor Protein, RAR related orphan receptor C Protein, RAR-related orphan receptor C Protein, RAR-related orphan receptor gamma Protein, RORC Protein, Rorc Protein

Hintergrund: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 58 kDa

NCBI Accession: NP_005051

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway