RNH1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730897

Produktdetails

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RNH1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Ribonuclease inhibitor (RNH1) (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Referenzen

Ascione, Rowlinson, Avolio, Katare, Meloni, Spencer, Mangialardi, Norris, Kränkel, Spinetti, Emanueli, Madeddu: "Migration towards SDF-1 selects angiogenin-expressing bone marrow monocytes endowed with cardiac reparative activity in patients with previous myocardial infarction." in: Stem cell research & therapy, Vol. 6, pp. 53, (2015) (PubMed).

Antigendetails

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Andere Bezeichnung: Ribonuclease Inhibitor (Rnh1) (RNH1 Produkte)

Synonyme: RAI Protein, RNH Protein, AW546468 Protein, C80305 Protein, RNH1 Protein, Rnh Protein, Rnh1 Protein, im:7039360 Protein, si:ch211-213a13.3 Protein, wu:fd55g05 Protein, ribonuclease/angiogenin inhibitor 1 Protein, ribonuclease inhibitor Protein, RNH1 Protein, Rnh1 Protein, Tc00.1047053511893.10 Protein, Tc00.1047053507583.70 Protein, rnh1 Protein

Hintergrund: Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010].

Molekulargewicht: 49.8 kDa

NCBI Accession: NP_002930