RAP1GAP Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730475

Produktdetails

Target: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 3

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RAP1GAP Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RAP1GAP (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Andere Bezeichnung: Rap1gap (RAP1GAP Produkte)

Synonyme: RAP1GA1 Protein, RAP1GAP1 Protein, RAP1GAPII Protein, RAPGAP Protein, 1300019I11Rik Protein, 2310004O14Rik Protein, AI427470 Protein, Rap1ga1 Protein, RAP1 Protein, RAP1GAP Protein, rap1ga1 Protein, rap1gap1 Protein, rap1gapii Protein, rapgap Protein, zgc:175180 Protein, DKFZp459A114 Protein, RAP1 GTPase activating protein Protein, Rap1 GTPase-activating protein Protein, RAP1 GTPase activating protein 1 Protein, RAP1 GTPase activating protein L homeolog Protein, Rap1 GTPase-activating protein 1 Protein, si:dkey-166d12.2 Protein, RAP1GAP Protein, Rap1gap Protein, RAP1GAP1 Protein, rap1gap.L Protein, Tsp_09520 Protein, rap1gap Protein, si:dkey-166d12.2 Protein

Hintergrund: This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Molekulargewicht: 73.2 kDa

NCBI Accession: NP_002876