RAP1A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730472

Produktdetails

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RAP1A Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RAP1A (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Andere Bezeichnung: Rap1a (RAP1A Produkte)

Synonyme: KREV-1 Protein, KREV1 Protein, RAP1 Protein, SMGP21 Protein, AI848598 Protein, G-22K Protein, Krev-1 Protein, Rap1 Protein, RAP-1A Protein, rap 1A Protein, wu:fc66g06 Protein, zgc:86676 Protein, krev-1 Protein, krev1 Protein, rap1 Protein, RAP1A, member of RAS oncogene family Protein, RAS-related protein 1a Protein, RAP1A, member of RAS oncogene family a Protein, RAP1A, member of RAS oncogene family L homeolog Protein, RAP1A Protein, Rap1a Protein, rap1aa Protein, rap1a.L Protein

Hintergrund: This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 20.8 kDa

NCBI Accession: NP_002875

Pathways: T-Zell Rezeptor Signalweg, Neurotrophin Signalübertragung, Signaling of Hepatocyte Growth Factor Receptor