RAD9A Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730420

Produktdetails

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RAD9A Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RAD9A protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Andere Bezeichnung: Rad9a (RAD9A Produkte)

Synonyme: RAD9 Protein, Rad9 Protein, rad9a Protein, MGC89062 Protein, XRad9 Protein, rad9 Protein, RAD9 checkpoint clamp component A Protein, RAD9 checkpoint clamp component B Protein, RAD9 checkpoint clamp component A L homeolog Protein, RAD9A Protein, Rad9a Protein, rad9a Protein, rad9b Protein, rad9a.L Protein

Hintergrund: This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 42.4 kDa

NCBI Accession: NP_004575

Pathways: Positive Regulation of Response to DNA Damage Stimulus