RAD51C Protein (His tag)

Produktnummer ABIN2730411

Produktdetails

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses RAD51C Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RAD51C (full length, N-term HIS tag, transcript variant 2) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Andere Bezeichnung: Rad51c (RAD51C Produkte)

Synonyme: RGD1563765 Protein, CG2412 Protein, Dm CG2412 Protein, Dmel\\CG2412 Protein, zgc:101596 Protein, RAD51C Protein, Rad51c Protein, ATRAD51C Protein, F4L23.21 Protein, RAS associated with diabetes protein 51C Protein, R51H3 Protein, Rad51l2 Protein, BROVCA3 Protein, FANCO Protein, RAD51L2 Protein, RAD51 paralog C Protein, Rad51 recombinase D Protein, Rad51 DNA recombinase 3 Protein, RAD51C protein Protein, RAD51 homolog C Protein, RAS associated with diabetes protein 51C Protein, RAD51C Protein, Rad51c Protein, Rad51D Protein, rad51c Protein

Hintergrund: This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 14.7 kDa

NCBI Accession: NP_002867

Pathways: DNA Reparatur