PC Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730237

Produktdetails

Target: PC (Pyruvate Carboxylase (PC))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 3

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PC Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Pyruvic carboxylase (PC) (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PC (Pyruvate Carboxylase (PC))

Andere Bezeichnung: Pyruvic Carboxylase (Pc) (PC Produkte)

Synonyme: BcDNA Protein, BcDNA:GH06348 Protein, Dmel\\CG1516 Protein, PC Protein, pyc Protein, wu:fb82g08 Protein, wu:fj85g01 Protein, PCX Protein, BA4157 Protein, Pc Protein, Pcb Protein, PCB Protein, Pcx Protein, Pyruvate carboxylase Protein, pyruvate carboxylase b Protein, PYruvate Carboxylase Protein, pyruvate carboxylase Protein, pyruvate carboxylase Pyr1 Protein, PCB Protein, pcxb Protein, pyc-1 Protein, PC Protein, pyc Protein, pyr1 Protein, CNF00650 Protein, PYC1 Protein, Ndas_1152 Protein, Ilyop_2503 Protein, Calni_0495 Protein, Ftrac_1004 Protein, Plabr_3574 Protein, Sgly_2936 Protein, Celly_0558 Protein, Hipma_0131 Protein, Halhy_1567 Protein, Mesop_1269 Protein, Pcx Protein, Pc Protein

Hintergrund: This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.

Molekulargewicht: 127.3 kDa

NCBI Accession: NP_001035806