PTRF Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730156

Produktdetails

Target: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PTRF Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PTRF protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Andere Bezeichnung: Ptrf (PTRF Produkte)

Synonyme: MGC53017 Protein, MGC89141 Protein, PTRF Protein, fd20g07 Protein, ptrf Protein, wu:fd20g07 Protein, zgc:162917 Protein, CAVIN Protein, CAVIN1 Protein, CGL4 Protein, cavin-1 Protein, 2310075E07Rik Protein, AW546441 Protein, Cav-p60 Protein, Cavin Protein, caveolae associated protein 1 L homeolog Protein, polymerase I and transcript release factor Protein, caveolae associated protein 1 Protein, caveolae associated protein 1b Protein, caveolae associated 1 Protein, cavin1.L Protein, PTRF Protein, cavin1 Protein, CAVIN1 Protein, cavin1b Protein, Cavin1 Protein

Hintergrund: This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.

Molekulargewicht: 43.3 kDa

NCBI Accession: NP_036364