PTPRO Protein (Transcript Variant 5) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730149

Produktdetails

Target: PTPRO (Protein tyrosine Phosphatase, Receptor Type, O (PTPRO))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 5

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PTPRO Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PTPRO (transcript variant 5) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PTPRO (Protein tyrosine Phosphatase, Receptor Type, O (PTPRO))

Andere Bezeichnung: Ptpro (PTPRO Produkte)

Synonyme: GLEPP1 Protein, RPTP-BK Protein, D28 Protein, PTPBK Protein, PTPROt Protein, PTPU2 Protein, PTPoc Protein, PTPphi Protein, Ptpn15 Protein, R-PTP-O Protein, NPHS6 Protein, PTP-OC Protein, PTP-U2 Protein, PTPROT Protein, protein tyrosine phosphatase, receptor type O Protein, protein tyrosine phosphatase, receptor type, O Protein, PTPRO Protein, Ptpro Protein

Hintergrund: This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer.

Molekulargewicht: 47 kDa

NCBI Accession: NP_109596

Pathways: Cell-Cell Junction Organization