PSPC1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730030

Produktdetails

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PSPC1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PSPC1 / PSP1 (transcript variant alpha) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Andere Bezeichnung: Pspc1,psp1 (PSPC1 Produkte)

Synonyme: rexp86 Protein, PSP1 Protein, fj85a06 Protein, wu:fj85a06 Protein, zgc:136470 Protein, 5730470C09Rik Protein, AI327109 Protein, AI449052 Protein, paraspeckle component 1 Protein, paraspeckle component 1 L homeolog Protein, paraspeckle protein 1 Protein, PSPC1 Protein, Tsp_01792 Protein, pspc1 Protein, pspc1.L Protein, Pspc1 Protein

Hintergrund: This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.

Molekulargewicht: 58.6 kDa

NCBI Accession: NP_001035879