PSMD8 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730007

Produktdetails

Target: PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PSMD8 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PSMD8 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))

Andere Bezeichnung: Psmd8 (PSMD8 Produkte)

Synonyme: HIP6 Protein, HYPF Protein, Nin1p Protein, Rpn12 Protein, S14 Protein, p31 Protein, hip6 Protein, hypf Protein, nin1p Protein, rpn12 Protein, psmd8b Protein, 6720456J22Rik Protein, AA407360 Protein, AL033291 Protein, AL033322 Protein, AL033323 Protein, C76433 Protein, psmd8 Protein, psmd8a Protein, fa93g07 Protein, fb17c09 Protein, fb49a10 Protein, zgc:86762 Protein, wu:fa93g07 Protein, wu:fb17c09 Protein, wu:fb49a10 Protein, PSMD8 Protein, proteasome 26S subunit, non-ATPase 8 Protein, proteasome 26S subunit, non-ATPase 8 S homeolog Protein, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 Protein, proteasome 26S subunit, non-ATPase 8 L homeolog Protein, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 pseudogene Protein, PSMD8 Protein, psmd8.S Protein, Psmd8 Protein, psmd8.L Protein, psmd8 Protein, LOC468490 Protein

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.

Molekulargewicht: 39.4 kDa

NCBI Accession: NP_002803

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Proton Transport, Synthesis of DNA, SARS-CoV-2 Protein Interaktom, Ubiquitin Proteasome Pathway