PRMT1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2729657

Produktdetails

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PRMT1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PRMT1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Referenzen

Tikhanovich, Kuravi, Artigues, Villar, Dorko, Nawabi, Roberts, Weinman: "Dynamic Arginine Methylation of Tumor Necrosis Factor (TNF) Receptor-associated Factor 6 Regulates Toll-like Receptor Signaling." in: The Journal of biological chemistry, Vol. 290, Issue 36, pp. 22236-49, (2015) (PubMed).

Antigendetails

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Andere Bezeichnung: Prmt1 (PRMT1 Produkte)

Synonyme: ANM1 Protein, HCP1 Protein, HRMT1L2 Protein, IR1B4 Protein, 6720434D09Rik Protein, AW214366 Protein, Hrmt1l2 Protein, Mrmt1 Protein, 3E10 Protein, anm1 Protein, hcp1 Protein, hrmt1l2 Protein, ir1b4 Protein, prmt1 Protein, prmt1b Protein, xPRMT1b Protein, xprmt1 Protein, xPRMT1 Protein, ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 1A Protein, ATPRMT1A Protein, F6F22.30 Protein, F6F22_30 Protein, protein arginine methyltransferase 1A Protein, DDBDRAFT_0183976 Protein, DDBDRAFT_0235399 Protein, DDB_0183976 Protein, DDB_0235399 Protein, PRMT1 Protein, DKFZp459J1326 Protein, fb39h07 Protein, wu:fb39h07 Protein, zf1 Protein, zgc:66201 Protein, protein arginine methyltransferase 1 Protein, protein arginine N-methyltransferase 1 Protein, protein arginine methyltransferase 1 L homeolog Protein, protein arginine methyltransferase 1 S homeolog Protein, protein arginine methyltransferase 1A Protein, protein arginine N-methyltransferase-1 Protein, protein arginine N-methyltransferase Protein, protein arginine methyltransferase Protein, PRMT1 Protein, Prmt1 Protein, prmt1.L Protein, prmt1.S Protein, PRMT1A Protein, prm-1 Protein, EDI_007800 Protein, Smp_029240.3 Protein, prmt1 Protein

Hintergrund: This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

Molekulargewicht: 42.3 kDa

NCBI Accession: NP_001527