PRAM1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2729546

Produktdetails

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PRAM1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PRAM1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Andere Bezeichnung: Pram1 (PRAM1 Produkte)

Synonyme: PRAM1 Protein, AY665714 Protein, PML-RAR Protein, PRAM-1 Protein, RGD1564330 Protein, PML-RARA regulated adaptor molecule 1 Protein, PML-RAR alpha-regulated adaptor molecule 1 Protein, PRAM1 Protein, Pram1 Protein

Hintergrund: The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).

Molekulargewicht: 73.7 kDa

NCBI Accession: NP_115528

Pathways: Regulation of Leukocyte Mediated Immunity