PPP1R16A Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2729476

Produktdetails

Target: PPP1R16A (Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PPP1R16A Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PPP1R16A / MYPT3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PPP1R16A (Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A))

Andere Bezeichnung: Ppp1r16a,mypt3 (PPP1R16A Produkte)

Synonyme: 2900084E10Rik Protein, Mypt3 Protein, R75527 Protein, MYPT3 Protein, protein phosphatase 1, regulatory (inhibitor) subunit 16A Protein, protein phosphatase 1 regulatory subunit 16A Protein, protein phosphatase 1, regulatory subunit 16A Protein, Ppp1r16a Protein, PPP1R16A Protein

Hintergrund: Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c.

Molekulargewicht: 57.6 kDa

NCBI Accession: NP_116291