Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PPARD Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

PPARD Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2729419
  • Target Alle PPARD Proteine anzeigen
    PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 4
    • 4
    • 1
    • 1
    Human
    Quelle
    • 4
    • 2
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses PPARD Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human PPAR-delta (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PPARD Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
    Andere Bezeichnung
    Ppar-delta (PPARD Produkte)
    Synonyme
    FAAR Protein, NR1C2 Protein, NUC1 Protein, NUCI Protein, NUCII Protein, PPARB Protein, NUC-1 Protein, Nr1c2 Protein, PPAR-beta Protein, PPAR-delta Protein, PPAR[b] Protein, PPARdelta Protein, Pparb Protein, Pparb/d Protein, PPARBETA Protein, ppard Protein, pparb Protein, PPARD Protein, PPAR-D/B Protein, peroxisome proliferator activated receptor delta Protein, peroxisome proliferator activator receptor delta Protein, peroxisome proliferator activated receptor delta S homeolog Protein, peroxisome proliferator-activated receptor delta Protein, PPARD Protein, Ppard Protein, ppard.S Protein, ppard Protein
    Hintergrund
    This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants.
    Molekulargewicht
    49.7 kDa
    NCBI Accession
    NP_006229
    Pathways
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
Sie sind hier:
Kundenservice