PF4 Protein

Produktnummer ABIN2729123

Produktdetails

Target: PF4 (Platelet Factor 4 (PF4))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)

Spezifität: Optimal preservation of protein structure, post-translational modifications and functions.

Produktmerkmale:

• Recombinant human Platelet factor 4 / PF4 protein expressed in E. coli.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Reinheit: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin-Niveau: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Biological Activity Comment: Determined by its ability to chemoattract human fibroblasts using a concentration range of 1.0-10.0 ng/ml.

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Handhabung: Resuspend the protein in the desired concentration in proper buffer

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PF4 (Platelet Factor 4 (PF4))

Andere Bezeichnung: Platelet Factor 4,pf4 (PF4 Produkte)

Synonyme: CXCL4 Protein, PF-4 Protein, SCYB4 Protein, Cxcl4 Protein, Scyb4 Protein, Pf4a Protein, RATPF4A Protein, PF4A Protein, CXCL4L1 Protein, CXCL4V1 Protein, PF4-ALT Protein, SCYB4V1 Protein, PF4 Protein, platelet factor 4 Protein, platelet factor 4 variant 1 Protein, PF4 Protein, Pf4 Protein, LOC703451 Protein, PF4V1 Protein, LOC100524373 Protein, LOC102181854 Protein, LOC100630489 Protein

Hintergrund: This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum.

Molekulargewicht: 7.8 kDa

NCBI Accession: NP_002610