Peroxiredoxin 3 Protein (PRDX3) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2728705

Produktdetails

Target: Peroxiredoxin 3 (PRDX3)

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Peroxiredoxin 3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Peroxiredoxin-3 / PRDX3 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Peroxiredoxin 3 (PRDX3)

Andere Bezeichnung: Peroxiredoxin-3,prdx3 (PRDX3 Produkte)

Synonyme: cb718 Protein, wu:fk49e09 Protein, zgc:110282 Protein, zgc:112512 Protein, MGC83969 Protein, PRDX3 Protein, AOP-1 Protein, AOP1 Protein, HBC189 Protein, MER5 Protein, PRO1748 Protein, SP-22 Protein, prx-III Protein, AW822249 Protein, Aop1 Protein, D0Tohi1 Protein, Ef2l Protein, Mer5 Protein, Prx3 Protein, SP22 Protein, TDXM Protein, MTAP Protein, peroxiredoxin 3 Protein, peroxiredoxin 3 S homeolog Protein, peroxiredoxin PRX3 Protein, prdx3 Protein, PRDX3 Protein, prdx3.S Protein, PRX3 Protein, Prdx3 Protein

Hintergrund: This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.

Molekulargewicht: 21.4 kDa

NCBI Accession: NP_006784

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process