PDE5A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2728518

Produktdetails

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PDE5A Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PDE5A (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Andere Bezeichnung: Pde5a (PDE5A Produkte)

Synonyme: CGB-PDE Protein, CN5A Protein, PDE5 Protein, PDE5A2 Protein, Cgbpde Protein, Cn5n Protein, Pde5 Protein, Pde5a1 Protein, PDE5A Protein, pde5a Protein, cgb-pde Protein, cn5a Protein, pde5 Protein, pde5a1 Protein, phosphodiesterase 5A Protein, phosphodiesterase 5A, cGMP-specific Protein, phosphodiesterase 5A S homeolog Protein, phosphodiesterase 5A, cGMP-specific, b Protein, PDE5A Protein, Pde5a Protein, pde5a.S Protein, pde5ab Protein, pde5a Protein

Hintergrund: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5&apos-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Molekulargewicht: 94.6 kDa

NCBI Accession: NP_236914

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling