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PDE4A Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

PDE4A Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2728507
  • Target Alle PDE4A Proteine anzeigen
    PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 4
    Spezies
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses PDE4A Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human PDE4A (transcript variant 4) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PDE4A Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Taniguchi, Iizumi, Watanabe, Masuda, Morita, Aono, Toriyama, Oishi, Goi, Sakai: "Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer." in: Cell death & disease, Vol. 7, pp. e2211, (2016) (PubMed).

  • Target
    PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
    Andere Bezeichnung
    Pde4a (PDE4A Produkte)
    Synonyme
    pde4 Protein, dpde2 Protein, pde46 Protein, PDE4A Protein, Pde4a Protein, D9Ertd60e Protein, Dpde2 Protein, DPDE2 Protein, PDE4 Protein, PDE46 Protein, PHOSA Protein, phosphodiesterase 4A S homeolog Protein, phosphodiesterase 4A, cAMP-specific Protein, phosphodiesterase 4A Protein, phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) Protein, cAMP-specific 3',5'-cyclic phosphodiesterase 4A Protein, phosphodiesterase 4A, cAMP specific Protein, phosphodiesterase 4C Protein, pde4a.S Protein, pde4a Protein, PDE4A Protein, LOC100009247 Protein, Pde4a Protein, PDE4C Protein
    Hintergrund
    The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].
    Molekulargewicht
    72 kDa
    NCBI Accession
    NP_006193
    Pathways
    cAMP Metabolic Process
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