PDE1C Protein (His tag)

Produktnummer ABIN2728485

Produktdetails

Target: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PDE1C Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PDE1C (N-term HIS tag, transcript variant 4) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 50 mM Tris,8M Urea, pH 8.0.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Andere Bezeichnung: Pde1c (PDE1C Produkte)

Synonyme: CG14940 Protein, CG14942 Protein, CG14943 Protein, CG14944 Protein, CG31757 Protein, CG31758 Protein, CG42325 Protein, CG44007 Protein, Dmel\\CG44007 Protein, Dmel_CG14940 Protein, Dmel_CG14943 Protein, Dmel_CG14944 Protein, Dmel_CG31757 Protein, Dmel_CG31758 Protein, Dmel_CG42325 Protein, PDE1C Protein, PDE1c Protein, GB13690 Protein, Hcam3 Protein, Phosphodiesterase 1c Protein, phosphodiesterase 1C Protein, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C Protein, phosphodiesterase 1C, calmodulin-dependent b Protein, Pde1c Protein, PDE1C Protein, LOC724389 Protein, LOC100019026 Protein, pde1cb Protein

Hintergrund: This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.

Molekulargewicht: 72 kDa

NCBI Accession: NP_005011

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma